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PRODID:talks.ox.ac.uk
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SUMMARY:Disentangling Genetics of Endometriosis and Adenomyosis with a foc
 us on Eastern Mediterranean Populations - Nura Fitnat Topbas Selcuki (Univ
 ersity of Oxford)
DTSTART;VALUE=DATE-TIME:20240924T130000
DTEND;VALUE=DATE-TIME:20240924T140000
UID:https://new.talks.ox.ac.uk/talks/id/cfe6da79-cb13-4ecb-b47a-b88f235131
 d1/
DESCRIPTION:Abstract:\nEndometriosis is a chronic inflammatory disease cha
 racterised by the presence of endometrial-like tissue outside of the uteru
 s. Similarly\, adenomyosis is defined by the presence of this tissue withi
 n in myometrium of the uterus. Both are disease of the uterus\, highly co-
 morbid but thought to have distinct disease mechanisms. The heritability o
 f endometriosis is estimated to be ~50% with ~26% risk attributed to commo
 n genetic variants. 42 genome-wide significant loci have been identified i
 n genome-wide association studies (GWAS)\; the majority being conducted am
 ong populations with European ancestry. To date no GWAS has been conducted
  for adenomyosis. I will present the results of the first adenomyosis GWAS
  meta-analysis conducted among white populations with European ancestry us
 ing UKBioBank\, FinnGen and All of Us datasets and compare these to endome
 triosis GWAS meta-analysis results. Then I will present two studies from E
 astern Mediterranean region\, COHERE from North Cyprus and TROX from Turki
 ye\, which have been initiated to expand the existing European based study
  cohorts to new ancestries.\n\n\nBio:\nI completed my medical degree at th
 e Heidelberg University in Germany and finished my training in Obstetrics 
 and Gynaecology in Istanbul Türkiye. During my training I got interested 
 in endometriosis and research in this field which led me to the EndoCare G
 roup. I am a final year DPhil student\, supervised by Nilufer Rahmioglu\, 
 Christian Becker and Krina Zondervan. I am also an active member of the En
 dometriosis and Adenomyosis Society Türkiye and the chair of the Early Ca
 reer Board of the World Endometriosis Society.\nSpeakers:\nNura Fitnat Top
 bas Selcuki (University of Oxford)
LOCATION:This event is hybrid
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/cfe6da79-cb13-4ecb-b47a-b88f235131
 d1/
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DESCRIPTION:Talk:Disentangling Genetics of Endometriosis and Adenomyosis w
 ith a focus on Eastern Mediterranean Populations - Nura Fitnat Topbas Selc
 uki (University of Oxford)
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