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SUMMARY:Patterns in Science and Art - Liliane Lijn\, Marcus du Sautoy and
Fatos Ustek with Conrad Shawcross - Liliane Lijn (Artist)\, Marcus du Sau
toy (University of Oxford)\, Fatos Ustek (Curator)\, Conrad Shawcross (Art
ist)
DTSTART;VALUE=DATE-TIME:20230928T173000
DTEND;VALUE=DATE-TIME:20230928T184500
UID:https://new.talks.ox.ac.uk/talks/id/be80dd8f-b82c-4088-99e2-b07bbfdf8b
60/
DESCRIPTION:The search for and creation of patterns is intrinsic to both s
cience and art. But so is the desire to understand how and why those patte
rns break down and to uncover the implications for the scientist and the a
rtist.\n\nArtist Liliane Lijn\, curator Fatos Ustek and mathematician Marc
us du Sautoy will share their experience and understanding of pattern and
where it has taken them in their scientific and artistic careers. Conrad S
hawcross will chair the discussion and provide his own unique perspective
as represented by his 'Cascading Principles' Exhibition.\n\nLiliane Lijn i
s an American-born artist who has exhibited at the Venice Biennale\, and w
as recently short listed for her design for the Fourth Plinth in Trafalgar
Square. Marcus Sautoy is a mathematician and Professor for the Public Und
erstanding of Science in Oxford. Fatos Ustek is curator of the 'Cascading
Principles' exhibition and curator of the sculpture park at Frieze London.
Conrad Shawcross is an artist specialising in mechanical sculptures based
on philosophical and scientific ideas.\nSpeakers:\nLiliane Lijn (Artist)\
, Marcus du Sautoy (University of Oxford)\, Fatos Ustek (Curator)\, Conrad
Shawcross (Artist)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/be80dd8f-b82c-4088-99e2-b07bbfdf8b
60/
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ACTION:display
DESCRIPTION:Talk:Patterns in Science and Art - Liliane Lijn\, Marcus du S
autoy and Fatos Ustek with Conrad Shawcross - Liliane Lijn (Artist)\, Marc
us du Sautoy (University of Oxford)\, Fatos Ustek (Curator)\, Conrad Shawc
ross (Artist)
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END:VEVENT
BEGIN:VEVENT
SUMMARY:Around the World in 80 Games - Marcus du Sautoy - Marcus du Sautoy
(University of Oxford)
DTSTART;VALUE=DATE-TIME:20231003T170000
DTEND;VALUE=DATE-TIME:20231003T180000
UID:https://new.talks.ox.ac.uk/talks/id/3fe2ca18-16ae-42f5-9511-438a8dfea9
8c/
DESCRIPTION:Join Marcus as he takes us on a mathematical journey across th
e centuries and through countries\, continents and cultures in search of t
he games we love to play. Based on his new book\, he looks at the way mat
hematics has always been deeply intertwined with games and investigates ho
w games themselves can provide us with opportunities for mathematical insi
ght into the world.\n\nFrom backgammon to chess\, Catan to Snakes and Ladd
ers\, games are not simply an enjoyable diversion. They are rather the hei
ght of human ingenuity. Ours is the species that loves playing games: not
homo sapiens but homo ludens. The lecture is suitable for everyone ‘from
age 8 to 108.’ Come and join Marcus on his journey Around the World in
80 Games. You simply can’t lose…\n\nMarcus du Sautoy is Charles Simon
yi Professor for the Public Understanding of Science in Oxford and Profess
or of Mathematics.\n\nPlease email external-relations@maths.ox.ac.uk to re
gister.\n\nThe lecture will be broadcast on the Oxford Mathematics YouTube
Channel on 24th October at 5pm and any time after.\n\nThe Oxford Mathemat
ics Public Lectures are generously supported by XTX Markets.\nSpeakers:\nM
arcus du Sautoy (University of Oxford)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/3fe2ca18-16ae-42f5-9511-438a8dfea9
8c/
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ACTION:display
DESCRIPTION:Talk:Around the World in 80 Games - Marcus du Sautoy - Marcus
du Sautoy (University of Oxford)
TRIGGER:-PT1H
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END:VEVENT
BEGIN:VEVENT
SUMMARY:Agent-based\, vertex-based\, and continuum modeling of cell behavi
or in biological patterns - Prof Alexandria Volkening (Department of Mathe
matics Weldon School of Biomedical Engineering)
DTSTART;VALUE=DATE-TIME:20231013T140000
DTEND;VALUE=DATE-TIME:20231013T150000
UID:https://new.talks.ox.ac.uk/talks/id/34017a7b-2cd1-40c9-907b-5325a6bb63
e7/
DESCRIPTION:Many natural and social phenomena involve individual agents co
ming together to create group dynamics\, whether the agents are drivers in
a traffic jam\, cells in a developing tissue\, or locusts in a swarm. Her
e I will focus on two examples of such emergent behavior in biology\, spec
ifically cell interactions during pattern formation in zebrafish skin and
gametophyte development in ferns. Different modeling approaches provide co
mplementary insights into these systems and face different challenges. For
example\, vertex-based models describe cell shape\, while more efficient
agent-based models treat cells as particles. Continuum models\, which trac
k the evolution of cell densities\, are more amenable to analysis\, but it
is often difficult to relate their few parameters to specific cell intera
ctions. In this talk\, I will overview our models of cell behavior in biol
ogical patterns and discuss our ongoing work on quantitatively relating di
fferent types of models using topological data analysis and data-driven te
chniques.\n\nSpeakers:\nProf Alexandria Volkening (Department of Mathemati
cs Weldon School of Biomedical Engineering)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/34017a7b-2cd1-40c9-907b-5325a6bb63
e7/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Agent-based\, vertex-based\, and continuum modeling of ce
ll behavior in biological patterns - Prof Alexandria Volkening (Department
of Mathematics Weldon School of Biomedical Engineering)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Machine learning for identifying translatable biomarkers and targe
ts - Professor Daphne Koller (Department of Computer Science Stanford Univ
ersity)
DTSTART;VALUE=DATE-TIME:20231020T150000
DTEND;VALUE=DATE-TIME:20231020T160000
UID:https://new.talks.ox.ac.uk/talks/id/ebbbd9b8-fee0-471f-ad72-58f57b8171
b2/
DESCRIPTION:Modern medicine has given us effective tools to treat some of
the most significant and burdensome diseases. At the same time\, it is bec
oming consistently more challenging and more expensive to develop new ther
apeutics. A key factor in this trend is that we simply don't understand th
e underlying biology of disease\, and which interventions might meaningful
ly modulate clinical outcomes and in which patients. To achieve this goal\
, we are bringing together large amounts of high content data\, taken both
from humans and from human-derived cellular systems generated in our own
lab. Those are then used to learn a meaningful representation of biologica
l states via cutting edge machine learning methods\, which enable us to ma
ke predictions about novel targets\, coherent patient segments\, and the c
linical effect of molecules. Our ultimate goal is to develop a new approac
h to drug development that uses high-quality data and ML models to design
novel\, safe\, and effective therapies that help more people\, faster\, an
d at a lower cost. \nSpeakers:\nProfessor Daphne Koller (Department of Com
puter Science Stanford University)
LOCATION:Mathematical Institute (Virtual)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/ebbbd9b8-fee0-471f-ad72-58f57b8171
b2/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Machine learning for identifying translatable biomarkers
and targets - Professor Daphne Koller (Department of Computer Science Stan
ford University)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Does Life know about quantum mechanics? - Jim Al-Khalili - Jim Al-
Khalili (University of Surrey)
DTSTART;VALUE=DATE-TIME:20231025T170000
DTEND;VALUE=DATE-TIME:20231025T180000
UID:https://new.talks.ox.ac.uk/talks/id/1ac60334-7826-4b95-a9ff-1427c45dd2
52/
DESCRIPTION:Oxford Mathematics Roger Penrose Public Lecture\n\nDoes Life k
now about quantum mechanics? - Jim Al-Khalili\n\nPhysicists and chemists a
re used to dealing with quantum mechanics\, but biologists have thus far g
ot away without having to worry about this strange yet powerful theory of
the subatomic world. However\, times are changing. There is now solid evid
ence that enzymes use quantum tunnelling to accelerate chemical reactions\
, while plants and bacteria use a quantum trick in photosynthesis – send
ing lumps of sunlight energy in multiple directions at once. It even appea
rs that some animals have the ability to use quantum entanglement – what
Einstein called “spooky action at a distance” – as a compass to ‘
see’ the earth’s magnetic field. In our research at the University of
Surrey we are discovering that life may even have evolved mechanisms to co
ntrol genetic mutations caused by quantum tunnelling of protons between st
rands of DNA. Welcome to the exciting new field of quantum biology.\n\nJim
Al-Khalili CBE FRS is an academic\, author and broadcaster. He holds a Di
stinguished Chair in Theoretical Physics at the University of Surrey where
he conducts research in quantum physics. He has written fifteen books on
popular science\, between them translated into over twenty-six languages.
He is a regular presenter of TV science documentaries and the long-running
BBC Radio 4 programme\, The Life Scientific.\n\nPlease email external-rel
ations@maths.ox.ac.uk to register to attend in person.\n\nThe lecture will
be broadcast on the Oxford Mathematics YouTube Channel on Wednesday 15 No
vember at 5pm and any time after (no need to register for the online versi
on).\n\nThe Oxford Mathematics Public Lectures are generously supported by
XTX Markets.\nSpeakers:\nJim Al-Khalili (University of Surrey)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/1ac60334-7826-4b95-a9ff-1427c45dd2
52/
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ACTION:display
DESCRIPTION:Talk:Does Life know about quantum mechanics? - Jim Al-Khalili
- Jim Al-Khalili (University of Surrey)
TRIGGER:-PT1H
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END:VEVENT
BEGIN:VEVENT
SUMMARY:Mathematical modelling throughout infectious disease outbreaks - D
r Robin Thompson (Mathematic Institute)
DTSTART;VALUE=DATE-TIME:20231027T140000
DTEND;VALUE=DATE-TIME:20231027T150000
UID:https://new.talks.ox.ac.uk/talks/id/9614e1d2-21af-43af-83e8-ac7b99d889
bd/
DESCRIPTION:Mathematical models are useful tools for guiding infectious di
sease outbreak control measures. Before a pathogen has even entered a host
population\, models can be used to determine the locations that are most
at risk of outbreaks\, allowing limited surveillance resources to be deplo
yed effectively. Early in an outbreak\, key questions for policy advisors
include whether initial cases will lead on to a major epidemic or fade out
as a minor outbreak. When a major epidemic is ongoing\, models can be app
lied to track pathogen transmissibility and inform interventions. And towa
rds the end of (or after) an outbreak\, models can be used to estimate the
probability that the outbreak is over and that no cases will be detected
in future\, with implications for when interventions can be lifted safely.
In this talk\, I will summarise the work done by my research group on mod
elling different stages of infectious disease outbreaks. This includes: i)
Before an outbreak: Projections of the locations at-risk from vector-born
e pathogens towards the end of the 21st century under a changing climate\;
ii) Early in an outbreak: Methods for estimating the risk that introduced
cases will lead to a major epidemic\; and iii) During a major epidemic: A
novel approach for inferring the time-dependent reproduction number durin
g outbreaks when disease incidence time series are aggregated temporally (
e.g. weekly case numbers are reported rather than daily case numbers). In
addition to discussing this work\, I will suggest areas for further resear
ch that will allow effective interventions to be planned during future inf
ectious disease outbreaks.\nSpeakers:\nDr Robin Thompson (Mathematic Insti
tute)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/9614e1d2-21af-43af-83e8-ac7b99d889
bd/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Mathematical modelling throughout infectious disease outb
reaks - Dr Robin Thompson (Mathematic Institute)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Leader\, follower\, and cheater in collective cancer invasion - Pr
ofessor Yi Jiang (College of Arts and Science Georgia State University)
DTSTART;VALUE=DATE-TIME:20231103T140000Z
DTEND;VALUE=DATE-TIME:20231103T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/c43a236e-4206-4bcd-af48-e6f2fadac1
5a/
DESCRIPTION:A major reason for the failure of cancer treatment and disease
progression is the heterogeneous composition of tumor cells at the geneti
c\, epigenetic\, and phenotypic levels. Despite extensive efforts to chara
cterize the makeup of individual cells\, there is still much to be learned
about the interactions between heterogeneous cancer cells and between can
cer cells and the microenvironment in the context of cancer invasion. Clin
ical studies and in vivo models have shown that cancer invasion predominan
tly occurs through collective invasion packs\, which invade more aggressiv
ely and result in worse outcomes. In vitro experiments on non-small cell l
ung cancer spheroids have demonstrated that the invasion packs consist of
leaders and followers who engage in mutualistic social interactions during
collective invasion. Many fundamental questions remain unanswered: What i
s the division of labor within the heterogeneous invasion pack? How does t
he leader phenotype emerge? Are the phenotypes plastic? What's the role of
the individual "cheaters"? How does the invasion pack interact with the s
troma? Can the social interaction network be exploited to devise novel tre
atment strategies? I will discuss recent modeling efforts to address these
questions and hope to convince you that identifying and perturbing the "w
eak links" within the social interaction network can disrupt collective in
vasion and potentially prevent the malignant progression of cancer. \nSpea
kers:\nProfessor Yi Jiang (College of Arts and Science Georgia State Unive
rsity)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/c43a236e-4206-4bcd-af48-e6f2fadac1
5a/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Leader\, follower\, and cheater in collective cancer inva
sion - Professor Yi Jiang (College of Arts and Science Georgia State Unive
rsity)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Forming a Thought into Form - Jon Keating\, Maya B. Kronic\, Emma
Ridgway\, and Conrad Shawcross with Fatos Ustek - Various (See programme)
DTSTART;VALUE=DATE-TIME:20231109T173000Z
DTEND;VALUE=DATE-TIME:20231109T183000Z
UID:https://new.talks.ox.ac.uk/talks/id/828447a1-c7b8-4ed8-b286-8e792d7adc
b0/
DESCRIPTION:Turning thought in to form is a mysterious process with which
artists\, scientists\, philosophers and\, indeed\, all of us engage. But t
hough the outcomes\, mathematical\, artistic\, philosophical\, may be diff
erent\, might there be much that is common to all?\n\nIn the last lecture
of the four-part series organised as part of Conrad Shawcross' 'Cascading
Principles' exhibition in Oxford Mathematics\, we bring together a panel c
omprising Jon Keating\, Sedleian Professor of Natural Philosophy at the Un
iversity of Oxford\, Emma Ridgway\, Director of the Foundling Museum\, M
aya B Kronicg\, philosopher and Director of Urbanomic\, and Conrad himself
. The discussion will be chaired by Fatos Ustek\, curator of the 'Cascad
ing Principles' exhibition.\n\nThere will be an opportunity to view the ex
hibition with the curator at 4pm on the day of the lecture.\n\nPlease emai
l external-relations@maths.ox.ac.uk to register for the in-person event.
The lecture will be broadcast on the Oxford Mathematics YouTube Channel
at a later date.\nSpeakers:\nVarious (See programme)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/828447a1-c7b8-4ed8-b286-8e792d7adc
b0/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Forming a Thought into Form - Jon Keating\, Maya B. Kroni
c\, Emma Ridgway\, and Conrad Shawcross with Fatos Ustek - Various (See p
rogramme)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Mathematical modelling identifies serum hepatitis B RNA as an info
rmative biomarker of anti-viral treatment efficacy - Dr Tyler Cassidy (Sch
ool of Mathematics University of Leeds)
DTSTART;VALUE=DATE-TIME:20231110T140000Z
DTEND;VALUE=DATE-TIME:20231110T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/64f4f35d-fec7-46a5-8bf7-b09e0e084b
fc/
DESCRIPTION:Chronic hepatitis B virus (HBV) infection leads to liver damag
e that increases the risk of hepatocellular carcinoma and liver cirrhosis.
Individuals with chronic HBV infection are often either treated with inte
rferon alpha or nucleoside reverse transcriptase inhibitors (NTRL). While
these NTRLs inhibit de novo DNA synthesis\, they do not represent a functi
onal cure for chronic HBV infection and so must be taken indefinitely. The
resulting life-long treatment leads to an increased risk of selection for
treatment resistant strains of HBV. Consequently\, there is increased int
erest in a novel treatment modality\, capsid protein allosteric modulators
(CPAMs)\, that blocks a crucial step in the viral life cycle. I'll discus
s recent work that identifies HBV serum RNA as an informative biomarker of
CPAM treatment efficacy\, evaluates CPAMs as a potential functional cure
for HBV infection\, and illustrates the role of mechanistic modelling in t
rial design using an age structured\, multi-scale mathematical model. \n\n
Speakers:\nDr Tyler Cassidy (School of Mathematics University of Leeds)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/64f4f35d-fec7-46a5-8bf7-b09e0e084b
fc/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Mathematical modelling identifies serum hepatitis B RNA a
s an informative biomarker of anti-viral treatment efficacy - Dr Tyler Cas
sidy (School of Mathematics University of Leeds)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:The generalist medical AI will see you now - Professor Pranav Raj
purkar (Department of Biomedical Informatics Harvard Medical School\, Bost
on)
DTSTART;VALUE=DATE-TIME:20231117T140000Z
DTEND;VALUE=DATE-TIME:20231117T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/2e715772-8007-475d-9647-8800578af5
32/
DESCRIPTION:Accurate interpretation of medical images is crucial for disea
se diagnosis and treatment\, and AI has the potential to minimize errors\,
reduce delays\, and improve accessibility. The focal point of this presen
tation lies in a grand ambition: the development of 'Generalist Medical AI
' systems that can closely resemble doctors in their ability to reason thr
ough a wide range of medical tasks\, incorporate multiple data modalities\
, and communicate in natural language. Starting with pioneering algorithms
that have already demonstrated their potential in diagnosing diseases fro
m chest X-rays or electrocardiograms\, matching the proficiency of expert
radiologists and cardiologists\, I will delve into the core challenges and
advancements in the field. The discussion will navigate towards the topic
of label-efficient AI models: with a scarcity of meticulously annotated d
ata in healthcare\, the development of AI systems capable of learning effe
ctively from limited labels has become a key concern. In this vein\, I'll
delve into how the innovative use of self-supervision and pre-training met
hods has led to algorithmic advancements that can perform high-level diagn
ostic tasks using significantly less annotated data. Additionally\, I will
talk about initiatives in data curation\, human-AI collaboration\, and th
e creation of open benchmarks to evaluate the generalizability of medical
AI algorithms. In sum\, this talk aims to deliver a comprehensive picture
of the state of 'Generalist Medical AI\,' the advancements made\, the chal
lenges faced\, and the prospects lying ahead. \nSpeakers:\nProfessor Prana
v Rajpurkar (Department of Biomedical Informatics Harvard Medical School\,
Boston)
LOCATION:Mathematical Institute (Virtual)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/2e715772-8007-475d-9647-8800578af5
32/
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ACTION:display
DESCRIPTION:Talk:The generalist medical AI will see you now - Professor P
ranav Rajpurkar (Department of Biomedical Informatics Harvard Medical Scho
ol\, Boston)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Advances in Advancing Interfaces: The Mathematics of Manufacturing
of Industrial Foams\, Fluidic Devices\, and Automobile Painting: The Sixt
eenth Brooke Benjamin Lecture 2023 - Professor James Sethian (University o
f California at Berkeley)
DTSTART;VALUE=DATE-TIME:20231121T170000Z
DTEND;VALUE=DATE-TIME:20231121T180000Z
UID:https://new.talks.ox.ac.uk/talks/id/4cfe53d8-d69e-4023-bbe3-87e8529704
af/
DESCRIPTION:Complex dynamics underlying industrial manufacturing depend in
part on multiphase multiphysics\, in which fluids and materials interact
across orders of magnitude variations in time and space. In this talk\, we
will discuss the development and application of a host of numerical metho
ds for these problems\, including Level Set Methods\, Voronoi Implicit Int
erface Methods\, implicit adaptive representations\, and multiphase discon
tinuous Galerkin Methods. Applications for industrial problems will inclu
de modeling how foams evolve\, how electro-fluid jetting devices work\, an
d the physics and dynamics of rotary bell spray painting across the automo
tive industry.\nSpeakers:\nProfessor James Sethian (University of Californ
ia at Berkeley)
LOCATION:Mathematical Institute (Lecture Room 1)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/4cfe53d8-d69e-4023-bbe3-87e8529704
af/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Advances in Advancing Interfaces: The Mathematics of Manu
facturing of Industrial Foams\, Fluidic Devices\, and Automobile Painting:
The Sixteenth Brooke Benjamin Lecture 2023 - Professor James Sethian (Uni
versity of California at Berkeley)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Mathematising certainty in the 18th century. Jacob Bernoulli’s a
nd Thomas Bayes’ redefinition of “absolute” and “moral” certaint
y through probability calculus - Dinh-Vinh Columban (Université Paris Nan
terre)
DTSTART;VALUE=DATE-TIME:20231122T171500Z
DTEND;VALUE=DATE-TIME:20231122T183000Z
UID:https://new.talks.ox.ac.uk/talks/id/0d9528cd-df9f-4fda-bd10-4590cb0498
b6/
DESCRIPTION:In the 17th century\, certainty was still largely organized ar
ound heterogeneous categories such as “absolute certainty” and “mora
l certainty”. “Absolute certainty” was the highest kind of certainty
rather than degree and it was limited to metaphysical and mathematical de
monstrations. On the other hand\, “moral certainty” was a high degree
of assent which\, even though it was subjective and always fallible\, was
regarded as sufficient for practical decisions based on empirical evidence
. Although this duality between “moral” and “absolute” certainty r
emained in use well into the 18th century\, its meaning shifted with the e
mergence of the calculus of probabilities. Probability calculus provided t
ools for attempts to mathematise “moral certainty” which would have be
en a contradiction in terms in their classical 17th-century sense.\n\nJaco
b Bernoulli's Ars Conjectandi (1713) followed by Thomas Bayes and Richard
Price's An Essay towards solving a Problem in the Doctrine of Chances (17
63) reshuffled what was before mutually exclusive characteristics of those
categories of certainty. Moral certainty became mathematizable and measur
able\, while absolute certainty would sit in continuity in degree with mor
al certainty rather than be different in kind. The concept of certainty as
a whole is thus redefined as a quantitative continuum.\n\nThis transforma
tion lays the conceptual foundations for a new approach to knowledge. Know
ledge and even scientific knowledge are no longer defined by a binary mode
l of an absolute exclusion of uncertainty\, but rather by the accuracy of
measurement of the irreducible uncertainty in all empirical-based knowledg
e. Such measurement becomes possible thanks to the new tools provided by t
he emergence of probability calculus.\nSpeakers:\nDinh-Vinh Columban (Univ
ersité Paris Nanterre)
LOCATION:The Queen's College (Magrath Room)\, High Street OX1 4AW
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/0d9528cd-df9f-4fda-bd10-4590cb0498
b6/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Mathematising certainty in the 18th century. Jacob Bernou
lli’s and Thomas Bayes’ redefinition of “absolute” and “moral”
certainty through probability calculus - Dinh-Vinh Columban (Université
Paris Nanterre)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:A Mathematical Journey through Literature - Sarah Hart - Sarah Har
t (Birkbeck\, University of London)
DTSTART;VALUE=DATE-TIME:20231123T170000Z
DTEND;VALUE=DATE-TIME:20231123T180000Z
UID:https://new.talks.ox.ac.uk/talks/id/3abcd2ee-0ea2-40d8-b323-c337285307
c7/
DESCRIPTION:In this lecture\, Sarah will explore the many connections betw
een mathematics and literature. She'll show the hidden mathematical struct
ures behind everything from poetry to novels\, and reveal some of the beau
tiful mathematical imagery and symbolism in fiction\, from simple fairy ta
les to classics like Moby-Dick. Her goal is to show that not only are mat
hematics and literature inextricably linked\, but that understanding these
links can enhance our enjoyment of both. \n\nSarah Hart is Professor of
Mathematics at Birkbeck\, University of London\, the Gresham Professor of
Geometry in Gresham College and author of Once Upon a Prime: the Wondrou
s Connections between Mathematics and Literature.\n\nPlease email external
-relations@maths.ox.ac.uk to register to attend in person.\n\nThe lecture
will be broadcast on the Oxford Mathematics YouTube Channel on Thursday
14th December at 5pm and any time after (no need to register for the onl
ine version).\n\nThe Oxford Mathematics Public Lectures are generously sup
ported by XTX Markets.\nSpeakers:\nSarah Hart (Birkbeck\, University of Lo
ndon)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/3abcd2ee-0ea2-40d8-b323-c337285307
c7/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:A Mathematical Journey through Literature - Sarah Hart -
Sarah Hart (Birkbeck\, University of London)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Using virtual clinical trials to improve our understanding of dise
ases - Professor Adrianne Jenner (Queensland University of Technology)
DTSTART;VALUE=DATE-TIME:20231124T140000Z
DTEND;VALUE=DATE-TIME:20231124T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/6b360af1-e609-468a-8ad4-cdbdee6574
90/
DESCRIPTION:Mathematical and computational techniques can improve our unde
rstanding of diseases. In this talk\, I’ll present ways in which data fr
om cancer patients can be combined with mathematical modelling and used to
improve cancer treatments. \nGiven the variability in individual response
s to cancer treatments\, agent-based modelling has been a useful technique
for accurately capturing cellular behaviours that may lead to stochastici
ty in patient outcomes. Using a hybrid agent-based model and partial diffe
rential equation system\, we developed a model for brain cancer (glioblast
oma) growth informed by ex-vivo patient samples. Extending the model to ca
pture patient treatment with an oncolytic virus rQNestin\, we used our mod
el to propose reasons for treatment failure\, which was later confirmed wi
th further patient samples. More recently\, we extended this model to inve
stigate the effectiveness of combination treatments (chemotherapy\, viroth
erapy and immunotherapy) informed by individual patient imaging mass cytom
etry. \nThis talk hopes to provide examples of ways mathematical and compu
tational modelling can be used to run “virtual” clinical trials with t
he goal of obtaining more effective treatments for diseases. \n\nSpeakers
:\nProfessor Adrianne Jenner (Queensland University of Technology)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/6b360af1-e609-468a-8ad4-cdbdee6574
90/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Using virtual clinical trials to improve our understandin
g of diseases - Professor Adrianne Jenner (Queensland University of Techno
logy)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Sequence models in biomedicine: from predicting disease progressio
n to genome editing outcomes - Professor Michael Krauthammer (Department o
f Quantitative Biomedicine University of Zurich)
DTSTART;VALUE=DATE-TIME:20231201T140000Z
DTEND;VALUE=DATE-TIME:20231201T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/20b57293-0c8c-4aaa-86ed-454c14a985
b4/
DESCRIPTION:Sequential biomedical data is ubiquitous\, from time-resolved
data about patient encounters in the clinical realm to DNA sequences in th
e biological domain. The talk will review our latest work in representati
on learning from longitudinal data\, with a particular focus on finding op
timal representations for complex and sparse healthcare data. We show how
these representations are useful for comparing patient journeys and findin
g patients with similar health outcomes. We will also venture into the fie
ld of genome engineering\, where we build models that work on DNA sequence
s for predicting editing outcomes for base and prime editors. \nSpeakers:\
nProfessor Michael Krauthammer (Department of Quantitative Biomedicine Uni
versity of Zurich)
LOCATION:Mathematical Institute (Virtual)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/20b57293-0c8c-4aaa-86ed-454c14a985
b4/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Sequence models in biomedicine: from predicting disease p
rogression to genome editing outcomes - Professor Michael Krauthammer (Dep
artment of Quantitative Biomedicine University of Zurich)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Modelling cells in one-dimension: diverse migration modes\, emerge
nt oscillations on junctions and multicellular "trains" - Professor Nir Go
v (Department of Chemical and Biological Physics Weizmann Institute of Sci
ence)
DTSTART;VALUE=DATE-TIME:20240119T140000Z
DTEND;VALUE=DATE-TIME:20240119T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/b9443bc9-2cd5-43a5-9267-309b7b7c0c
d7/
DESCRIPTION:Motile cells inside living tissues often encounter junctions\,
where their path branches into several alternative directions of migratio
n. We present a theoretical model of cellular polarization for cells migra
ting along one-dimensional lines\, exhibiting diverse migration modes. Whe
n arriving at a symmetric Y-junction and extending protrusions along the d
ifferent paths that emanate from the junction. The model predicts the spon
taneous emergence of deterministic oscillations between competing protrusi
ons\, whereby the cellular polarization and growth alternates between the
competing protrusions. These predicted oscillations are found experimental
ly for two different cell types\, noncancerous endothelial and cancerous g
lioma cells\, migrating on patterned network of thin adhesive lanes with j
unctions. Finally we present an analysis of the migration modes of multice
llular "trains" along one-dimensional tracks.\nSpeakers:\nProfessor Nir Go
v (Department of Chemical and Biological Physics Weizmann Institute of Sci
ence)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/b9443bc9-2cd5-43a5-9267-309b7b7c0c
d7/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Modelling cells in one-dimension: diverse migration modes
\, emergent oscillations on junctions and multicellular "trains" - Profess
or Nir Gov (Department of Chemical and Biological Physics Weizmann Institu
te of Science)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:The hitchhiker's guide to complex models of intracellular signalli
ng - Professor Fabian Frohlich (The Francis Crick Institute)
DTSTART;VALUE=DATE-TIME:20240126T140000Z
DTEND;VALUE=DATE-TIME:20240126T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/100682a7-874a-4a34-9a53-273f50b7cb
87/
DESCRIPTION:Unraveling the intricacies of intracellular signalling through
predictive mathematical models holds great promise for advancing precisio
n medicine and enhancing our foundational comprehension of biology. Howeve
r\, navigating the labyrinth of biological mechanisms governing signalling
demands a delicate balance between a faithful description of the underlyi
ng biology and the practical utility of parsimonious models.\nIn this talk
\, I will present methods that enable training of large ordinary different
ial equation models of intracellular signalling and showcase application o
f such models to predict sensitivity to anti-cancer drugs. Through illustr
ative examples\, I will demonstrate the application of these models in pre
dicting sensitivity to anti-cancer drugs. A critical reflection on the con
struction of such models will be offered\, exploring the perpetual questio
n of complexity and how intricate these models should be.\nMoreover\, the
talk will explore novel approaches that meld machine learning techniques w
ith mathematical modelling. These approaches aim to harness the benefits o
f simplistic and unbiased phenomenological models while retaining the inte
rpretability and biological fidelity inherent in mechanistic models.\n\nSp
eakers:\nProfessor Fabian Frohlich (The Francis Crick Institute)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/100682a7-874a-4a34-9a53-273f50b7cb
87/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:The hitchhiker's guide to complex models of intracellular
signalling - Professor Fabian Frohlich (The Francis Crick Institute)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:From individual-based models to continuum descriptions: Modelling
and analysis of interactions between different populations. - Dr Mariya Pt
ashnyk (Dept of Maths Herriot Watt University)
DTSTART;VALUE=DATE-TIME:20240212T163000Z
DTEND;VALUE=DATE-TIME:20240212T173000Z
UID:https://new.talks.ox.ac.uk/talks/id/ed2c53fa-2f81-443e-ad89-dc83bafe1f
1a/
DESCRIPTION:First we will show that the continuum counterpart of the discr
ete individual-based mechanical model that describes the dynamics of two c
ontiguous cell populations is given by a free-boundary problem for the cel
l densities. Then\, in addition to interactions\, we will consider the mi
croscopic movement of cells and derive a fractional cross-diffusion system
as the many-particle limit of a multi-species system of moderately intera
cting particles.\nSpeakers:\nDr Mariya Ptashnyk (Dept of Maths Herriot Wat
t University)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/ed2c53fa-2f81-443e-ad89-dc83bafe1f
1a/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:From individual-based models to continuum descriptions: M
odelling and analysis of interactions between different populations. - Dr
Mariya Ptashnyk (Dept of Maths Herriot Watt University)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Logging the World - Oliver Johnson - Oliver Johnson (University of
Bristol)
DTSTART;VALUE=DATE-TIME:20240214T170000Z
DTEND;VALUE=DATE-TIME:20240214T180000Z
UID:https://new.talks.ox.ac.uk/talks/id/285f350a-7125-41c9-9feb-0aaeca29cc
2e/
DESCRIPTION:Oxford Mathematics Public Lecture: Logging the World - Oliver
Johnson\n\nDuring the pandemic\, you may have seen graphs of data plotted
on strange-looking (logarithmic) scales. Oliver will explain some of the b
asics and history of logarithms\, and show why they are a natural tool to
represent numbers ranging from COVID data to Instagram followers. In fact\
, we’ll see how logarithms can even help us understand information itsel
f in a mathematical way.\n\nOliver Johnson is Professor of Information The
ory in the School of Mathematics at the University of Bristol where his re
search involves randomness and uncertainty. During the pandemic he became
a commentator on the daily COVID numbers\, through his Twitter account and
through appearances on Radio 4 and articles for the Spectator. He is the
author of the book Numbercrunch (2023)\, which is designed to help a gener
al audience understand the value of maths as a toolkit for making sense of
the world.\n\nPlease email external-relations@maths.ox.ac.uk to register
to attend in person.\n\nThe lecture will be broadcast on the Oxford Mathem
atics YouTube Channel on Wednesday 06 March at 5-6pm and any time after (n
o need to register for the online version).\n\nThe Oxford Mathematics Publ
ic Lectures are generously supported by XTX Markets.\nSpeakers:\nOliver Jo
hnson (University of Bristol)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/285f350a-7125-41c9-9feb-0aaeca29cc
2e/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Logging the World - Oliver Johnson - Oliver Johnson (Univ
ersity of Bristol)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Active surfaces in biology - Professor Alex Mietke (Dept of Physic
s\, University of Oxford)
DTSTART;VALUE=DATE-TIME:20240216T140000Z
DTEND;VALUE=DATE-TIME:20240216T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/37599009-e340-4c53-b965-0e346c1646
be/
DESCRIPTION:The ability of biological matter to move and deform itself is
facilitated by microscopic out-of-equilibrium processes that convert chemi
cal energy into mechanical work. In many cases\, this mechano-chemical act
ivity takes place on effectively two-dimensional domains formed by\, for e
xample\, multicellular structures like epithelial tissues or the outer sur
face of eukaryotic cells\, the so-called actomyosin cortex. We will show i
n the first part of the talk\, that the large-scale dynamics and self-orga
nisation of such structures can be captured by the theory of active fluids
. Specifically\, using a minimal model of active isotropic fluids\, we can
rationalize the emergence of asymmetric epithelial tissue flows in the fl
ower beetle during early development\, and explain cell rotations in the c
ontext of active chiral flows and left-right symmetry breaking that occurs
as the model organism C. elegans sets up its body plan. To develop a more
general understanding of such processes\, specifically the role of geomet
ry\, curvature and interactions with the environment\, we introduce in the
second part a theory of active fluid surfaces and discuss analytical and
numerical tools to solve the corresponding momentum balance equations of c
urved and deforming surfaces. By considering mechanical interactions with
the environment and the fully self-organized shape dynamics of active surf
aces\, these tools reveal novel mechanisms of symmetry breaking and patter
n formation in active matter.\nSpeakers:\nProfessor Alex Mietke (Dept of P
hysics\, University of Oxford)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/37599009-e340-4c53-b965-0e346c1646
be/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Active surfaces in biology - Professor Alex Mietke (Dept
of Physics\, University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Structural identifiability analysis: An important tool in systems
modelling - Professor Michael Chappell (University of Warwick)
DTSTART;VALUE=DATE-TIME:20240222T120000Z
DTEND;VALUE=DATE-TIME:20240222T130000Z
UID:https://new.talks.ox.ac.uk/talks/id/182dd420-e500-4d05-a55f-c509ee06fa
a8/
DESCRIPTION:For many systems (certainly those in biology\, medicine and ph
armacology) the mathematical models that are generated invariably include
state variables that cannot be directly measured and associated model para
meters\, many of which may be unknown\, and which also cannot be measured.
For such systems there is also often limited access for inputs or pertur
bations. These limitations can cause immense problems when investigating
the existence of hidden pathways or attempting to estimate unknown paramet
ers and this can severely hinder model validation. It is therefore highly
desirable to have a formal approach to determine what additional inputs a
nd/or measurements are necessary in order to reduce or remove these limita
tions and permit the derivation of models that can be used for practical p
urposes with greater confidence.\nStructural identifiability arises in the
inverse problem of inferring from the known\, or assumed\, properties of
a biomedical or biological system a suitable model structure and estimates
for the corresponding rate constants and other model parameters. Structu
ral identifiability analysis considers the uniqueness of the unknown model
parameters from the input-output structure corresponding to proposed expe
riments to collect data for parameter estimation (under an assumption of t
he availability of continuous\, noise-free observations). This is an impo
rtant\, but often overlooked\, theoretical prerequisite to experiment desi
gn\, system identification and parameter estimation\, since estimates for
unidentifiable parameters are effectively meaningless. If parameter estim
ates are to be used to inform about intervention or inhibition strategies\
, or other critical decisions\, then it is essential that the parameters b
e uniquely identifiable. \nNumerous techniques for performing a structural
identifiability analysis on linear parametric models exist and this is a
well-understood topic. In comparison\, there are relatively few technique
s available for nonlinear systems (the Taylor series approach\, similarity
transformation-based approaches\, differential algebra techniques and the
more recent observable normal form approach and symmetries approaches) an
d significant (symbolic) computational problems can arise\, even for relat
ively simple models in applying these techniques.\nIn this talk an introdu
ction to structural identifiability analysis will be provided demonstratin
g the application of the techniques available to both linear and nonlinear
parameterised systems and to models of (nonlinear mixed effects) populati
on nature.\n\nIn this talk an introduction to structural identifiability a
nalysis will be provided demonstrating the application of the techniques a
vailable to both linear and nonlinear parameterised systems and to models
of (nonlinear mixed effects) population nature.\n\nSpeakers:\nProfessor Mi
chael Chappell (University of Warwick)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/182dd420-e500-4d05-a55f-c509ee06fa
a8/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Structural identifiability analysis: An important tool in
systems modelling - Professor Michael Chappell (University of Warwick)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Mobilizing Mathematics for the Fight Against Cancer - Trachette Ja
ckson - Trachette Jackson (University of Michigan)
DTSTART;VALUE=DATE-TIME:20240229T170000Z
DTEND;VALUE=DATE-TIME:20240229T180000Z
UID:https://new.talks.ox.ac.uk/talks/id/5e51be93-1507-4c20-9367-f3a8182e29
4d/
DESCRIPTION:Mathematical oncologists apply mathematical and computational
models to every aspect of cancer biology\, from tumor initiation to malign
ant spread and treatment response. A substantial amount of medical researc
h now focuses on the molecular biology of individual tumors to selectively
target pathways involved in tumor progression\, leading to careful manipu
lation of these pathways\, and new cell-specific approaches to cancer ther
apy are now being developed. At the same time\, advances in cancer immunot
herapies have led to a reemergence of their use and effectiveness. Using d
ata-driven computational models is a powerful and practical way to investi
gate the therapeutic potential of novel combinations of these two very dif
ferent strategies for clinical cancer treatment.\n\nTrachette will showcas
e mathematical models designed to optimize targeted drug treatment strateg
ies in combination with immunotherapy\, to gain a more robust understandin
g of how specific tumor mutations affect the immune system and ultimately
impact combination therapy. Combined with existing and newly generated exp
erimental data\, these models are poised to improve the ability to connect
promising drugs for clinical trials and reduce the time and costs of tran
sitioning novel therapeutic approaches from “equations to bench to bedsi
de.”\n\nTrachette Jackson is Professor of Mathematics at the University
of Michigan and recipient of many awards for her work in her field and for
her commitment to increasing opportunities for girls\, women\, and underr
epresented minority students.\n\nPlease email external-relations@maths.ox.
ac.uk to register to attend in person.\n\nThe lecture will be broadcast on
the Oxford Mathematics YouTube Channel on Thursday 21 March at 5-6pm and
any time after (no need to register for the online version).\n\nThe Oxford
Mathematics Public Lectures are generously supported by XTX Markets.\nSpe
akers:\nTrachette Jackson (University of Michigan)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/5e51be93-1507-4c20-9367-f3a8182e29
4d/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Mobilizing Mathematics for the Fight Against Cancer - Tra
chette Jackson - Trachette Jackson (University of Michigan)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Extreme pushed and pulled fronts - Professor John King (School of
Mathematical Sciences\, University of Nottingham)
DTSTART;VALUE=DATE-TIME:20240301T140000Z
DTEND;VALUE=DATE-TIME:20240301T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/3c059422-ba4c-47cb-aa5f-122c9d0656
95/
DESCRIPTION:I shall say some stuff about quasilinear reaction-diffusion eq
uations\, motivated by tissue growth in particular.\nSpeakers:\nProfessor
John King (School of Mathematical Sciences\, University of Nottingham)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/3c059422-ba4c-47cb-aa5f-122c9d0656
95/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Extreme pushed and pulled fronts - Professor John King (S
chool of Mathematical Sciences\, University of Nottingham)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:The Conceptualization of Mathematics in Pharaonic Egypt - Annette
Imhausen (Goethe-Universität Frankfurt)
DTSTART;VALUE=DATE-TIME:20240306T170000Z
DTEND;VALUE=DATE-TIME:20240306T183000Z
UID:https://new.talks.ox.ac.uk/talks/id/1ce62f28-b786-4c24-8e86-a47a70e07d
17/
DESCRIPTION:Ancient Egypt is credited (along with Mesopotamia) for providi
ng the oldest extant mathematical texts. Since the 19th century\, when the
first edition of the Rhind mathematical papyrus was published\, it has he
ld an important role in the historiography of mathematics. One of the earl
iest researchers in the field of ancient Egyptian sciences was Otto Neugeb
auer who has been a major influence on the early development of the field.
While research in Egyptian mathematics initially focused on those aspects
that could be linked to its possible successors in modern mathematics\, r
esearch has also revealed various characteristics that could not easily be
transferred into a modern equivalent. In addition\, research on other sci
ences\, like medicine and astronomy\, has yielded further evidence that a
limitation on those aspects that have successors in modern sciences will a
t best give an incomplete picture of ancient scholarship. This will be exp
lored in a new long-term project\, which is briefly sketched. In the conte
xt of this project\, Egyptian mathematics is also studied. The talk will p
resent an example from the terminology used in Egyptian mathematical texts
to describe this area of knowledge and explore its epistemological conseq
uences for our studies of ancient Egyptian mathematics and aim to situate
it in its ancient context.\nSpeakers:\nAnnette Imhausen (Goethe-Universit
ät Frankfurt)
LOCATION:Mathematical Institute (Lecture Room L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/1ce62f28-b786-4c24-8e86-a47a70e07d
17/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:The Conceptualization of Mathematics in Pharaonic Egypt -
Annette Imhausen (Goethe-Universität Frankfurt)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Modeling multiscale systems in bone mechanobiology - Professor
Esther Reina Romo (Department of Mechanical Engineering ETSI\, University
of Seville)
DTSTART;VALUE=DATE-TIME:20240308T140000Z
DTEND;VALUE=DATE-TIME:20240308T150000Z
UID:https://new.talks.ox.ac.uk/talks/id/8c70e9f7-86e4-49f0-94e7-2493620458
21/
DESCRIPTION:Bone regeneration processes are complex multiscale intrinsic m
echanisms in bone tissue whose primary outcome is restoring function and f
orm to a bone insufficiency. The effect of mechanics on the newly formed b
one (the woven bone)\, is fundamental\, at the tissue\, cellular or even m
olecular scale. However\, at these multiple scales\, the identification of
the mechanical parameters and their mechanisms of action are still unknow
n and continue to be investigated. This concept of mechanical regulation o
f biological processes is the main premise of mechanobiology and is used i
n this seminar to understand the multiscale response of the woven bone to
mechanical factors in different bone regeneration processes: bone transpor
t\, bone lengthening and tissue engineering. The importance of a multidisc
iplinary approach that includes both in vivo and in silico modeling will b
e remarked during the seminar.\nSpeakers:\nProfessor Esther Reina Romo (De
partment of Mechanical Engineering ETSI\, University of Seville)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/8c70e9f7-86e4-49f0-94e7-2493620458
21/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Modeling multiscale systems in bone mechanobiology -
Professor Esther Reina Romo (Department of Mechanical Engineering ETSI\, U
niversity of Seville)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:The Ubiquity of Braids - Tara Brendle - Tara Brendle (University o
f Glasgow)
DTSTART;VALUE=DATE-TIME:20240425T170000
DTEND;VALUE=DATE-TIME:20240425T180000
UID:https://new.talks.ox.ac.uk/talks/id/43af48e3-d054-48c8-8159-e18852ca3b
c9/
DESCRIPTION:What do maypole dancing\, grocery delivery\, and the quadratic
formula all have in common? The answer is: braids! In this talk Tara will
explore how the ancient art of weaving strands together manifests itself
in a variety of modern settings\, both within mathematics and in our wider
culture. \n\nTara Brendle is a Professor of Mathematics in the School
of Mathematics & Statistics at the University of Glasgow. Her research lie
s in the area of geometric group theory\, at the interface between algebra
and topology. She is co-author of 'Braids: A Survey'\, appearing in 'The
Handbook of Knot Theory'.\n\nPlease email external-relations@maths.ox.ac.u
k to attend in person.\n\nThe lecture will be broadcast on the Oxford Math
ematics YouTube Channel (https://www.youtube.com/c/OxfordMathematics) on T
hursday 16 May at 5-6pm and any time after (no need to register for the on
line version).\n\nThe Oxford Mathematics Public Lectures are generously su
pported by XTX Markets.\nSpeakers:\nTara Brendle (University of Glasgow)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/43af48e3-d054-48c8-8159-e18852ca3b
c9/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:The Ubiquity of Braids - Tara Brendle - Tara Brendle (Uni
versity of Glasgow)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Polynomial dynamical systems and reaction networks: persistence an
d global attractors - Professor Gheorghe Craciun (Department of Mathemati
cs and Department of Biomolecular Chemistry\, University of Wisconsin-Madi
son)
DTSTART;VALUE=DATE-TIME:20240426T140000
DTEND;VALUE=DATE-TIME:20240426T150000
UID:https://new.talks.ox.ac.uk/talks/id/4db33b0f-4b71-4d8a-b7c3-5c24cd4e4d
4a/
DESCRIPTION:The mathematical analysis of global properties of polynomial d
ynamical systems can be very challenging (for example: the second part of
Hilbert’s 16th problem about polynomial dynamical systems in 2D\, or the
analysis of chaotic dynamics in the Lorenz system).\nOn the other hand\,
any dynamical system with polynomial right-hand side can essentially be re
garded as a model of a reaction network. Key properties of reaction system
s are closely related to fundamental results about global stability in cla
ssical thermodynamics. For example\, the Global Attractor Conjecture can b
e regarded as a finite dimensional version of Boltzmann’s H-theorem. We
will discuss some of these connections\, as well as the introduction of to
ric differential inclusions as a tool for proving the Global Attractor Con
jecture.\nWe will also discuss some implications for the more general Pers
istence Conjecture (which says that solutions of weakly reversible systems
cannot "go extinct")\, as well as some applications to biochemical mechan
isms that implement cellular homeostasis. \n\nSpeakers:\nProfessor Gheorgh
e Craciun (Department of Mathematics and Department of Biomolecular Chemis
try\, University of Wisconsin-Madison)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/4db33b0f-4b71-4d8a-b7c3-5c24cd4e4d
4a/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Polynomial dynamical systems and reaction networks: persi
stence and global attractors - Professor Gheorghe Craciun (Department of
Mathematics and Department of Biomolecular Chemistry\, University of Wisco
nsin-Madison)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Epidemiological modelling with behavioural considerations and to i
nform policy making - Dr Edward Hill (Dept of Mathematics\, University of
Warwick)
DTSTART;VALUE=DATE-TIME:20240503T140000
DTEND;VALUE=DATE-TIME:20240503T150000
UID:https://new.talks.ox.ac.uk/talks/id/6f4961eb-d329-4a7c-ac7d-bbdba0c392
85/
DESCRIPTION:Many problems in epidemiology are impacted by behavioural dyna
mics\, whilst in response to health emergencies prompt analysis and commun
ication of findings is required to be of use to decision makers. Both inst
ances are likely to benefit from interdisciplinary approaches. This talk w
ill feature two examples\, one with a public health focus and one with a v
eterinary health focus.\n\nIn the first part\, I will summarise work origi
nally conducted in late 2020 that was contributed to Scientific Pandemic I
nfluenza Group on Modelling\, Operational sub-group (SPI-M-O) of SAGE (Sci
entific Advisory Group for Emergencies) on Christmas household bubbles in
England. This was carried out in response to a policy involving a planned
easing of restrictions in England between 23–27 December 2020\, with Chr
istmas bubbles allowing people from up to three households to meet through
out the holiday period. Using a household model and computational simulati
on\, we estimated the epidemiological impact of both this and alternative
bubble strategies that allowed extending contacts beyond the immediate hou
sehold.\n\n(Associated paper: Modelling the epidemiological implications f
or SARS-CoV-2 of Christmas household bubbles in England in December 2020.
https://doi.org/10.1016/j.jtbi.2022.111331)\n\nIn the second part\, I will
present a methodological pipeline developed to generate novel quantitativ
e data on farmer beliefs with respect to disease management\, process the
data into a form amenable for use in mathematical models of livestock dise
ase transmission and then refine said mathematical models according to the
findings of the data. Such an approach is motivated by livestock disease
models traditionally omitting variation in farmer disease management behav
iours. I will discuss our application of this methodology for a fast\, spa
tially spreading disease outbreak scenario amongst cattle herds in Great B
ritain\, for which we elicited when farmers would use an available vaccine
and then used the attained behavioural groups within a livestock disease
model to make epidemiological and health economic assessments. \n\n(Associ
ated paper: Incorporating heterogeneity in farmer disease control behaviou
r into a livestock disease transmission model. https://doi.org/10.1016/j.p
revetmed.2023.106019)\nSpeakers:\nDr Edward Hill (Dept of Mathematics\, Un
iversity of Warwick)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/6f4961eb-d329-4a7c-ac7d-bbdba0c392
85/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Epidemiological modelling with behavioural considerations
and to inform policy making - Dr Edward Hill (Dept of Mathematics\, Unive
rsity of Warwick)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY: The determining role of cell adhesions for force transmission\, m
echanical activity and stiffness sensing in cells and tissues - Dr Carina
Edwards (School of Mathematics & Physics\, University of Surrey)
DTSTART;VALUE=DATE-TIME:20240510T140000
DTEND;VALUE=DATE-TIME:20240510T150000
UID:https://new.talks.ox.ac.uk/talks/id/eb8006a0-50df-4855-95e9-8f621429a7
e4/
DESCRIPTION:The role of tissue stiffness in controlling cell behaviours ra
nging from proliferation to signalling and activation is by now well accep
ted. A key focus of experimental studies into mechanotransduction are foca
l adhesions\, localised patches of strong adhesion\, where cell signalling
has been established to occur. However\, these adhesion sites themselves
alter the mechanical equilibrium of the system determining the force balan
ce and work done. To explore this I have developed an active matter contin
uum description of cellular contractility and will discuss recent results
on the specific role of spatial positioning of adhesions in mechanotransdu
ction. I show using energy arguments why the experimentally observed arran
gements of focal adhesions develop and the implications this has for stiff
ness sensing and cellular contractility control. I will also show how adhe
sions play distinct roles in single cells and tissue layers respectively d
rawing on recent experimental work with Dr JR Davis (Manchester University
) and Dr Nic Tapon (Crick Institute) with applications to epithelial layer
s and organoids.\nSpeakers:\nDr Carina Edwards (School of Mathematics & Ph
ysics\, University of Surrey)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/eb8006a0-50df-4855-95e9-8f621429a7
e4/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk: The determining role of cell adhesions for force transmi
ssion\, mechanical activity and stiffness sensing in cells and tissues - D
r Carina Edwards (School of Mathematics & Physics\, University of Surrey)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Some consequences of phenotypic heterogeneity in living active mat
ter - Dr Philip Pearce (Dept of Mathematics\, UCL)
DTSTART;VALUE=DATE-TIME:20240517T140000
DTEND;VALUE=DATE-TIME:20240517T150000
UID:https://new.talks.ox.ac.uk/talks/id/42f8eeaf-e288-4b9b-bbe7-b97a7cd1ce
41/
DESCRIPTION:In this talk I will discuss how phenotypic heterogeneity affec
ts emergent pattern formation in living active matter with chemical commun
ication between cells. In doing so\, I will explore how the emergent dynam
ics of multicellular communities are qualitatively different in comparison
to the dynamics of isolated or non-interacting cells. I will focus on two
specific projects. First\, I will show how genetic regulation of chemical
communication affects motility-induced phase separation in cell populatio
ns. Second\, I will demonstrate how chemotaxis along self-generated signal
gradients affects cell populations undergoing 3D morphogenesis.\nSpeakers
:\nDr Philip Pearce (Dept of Mathematics\, UCL)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/42f8eeaf-e288-4b9b-bbe7-b97a7cd1ce
41/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Some consequences of phenotypic heterogeneity in living a
ctive matter - Dr Philip Pearce (Dept of Mathematics\, UCL)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Infinite Jesters: what can philosophers learn from a puzzle involv
ing infinitely many clowns? - Ofra Magidor and Alexander Kaiserman - Ofra
Magidor (University of Oxford)
DTSTART;VALUE=DATE-TIME:20240523T170000
DTEND;VALUE=DATE-TIME:20240523T180000
UID:https://new.talks.ox.ac.uk/talks/id/c9ae6a63-a1c9-4539-bb79-24fbd931c0
46/
DESCRIPTION:Ofra and Alex consider a simple but intriguing mathematical ar
gument\, which purports to show how infinitely many clowns appear to have
some surprising powers. They'll discuss what conclusions philosophers can
and cannot draw from this case\, and connect the discussion to a number of
key philosophical issues such as the problem of free will and the Grandfa
ther Paradox for time travel.\n\nOfra Magidor is Waynflete Professor of Me
taphysical Philosophy at the University of Oxford and Fellow of Magdalen C
ollege. Alex Kaiserman is Associate Professor of Philosophy at the Univers
ity of Oxford and Fairfax Fellow and Tutor in Philosophy at Balliol Colleg
e. While they are both philosophers\, Ofra holds a BSc in Philosophy\, Mat
hematics\, and Computer Science and Alex holds an MPhysPhil in Physics and
Philosophy\, so they are no strangers to STEM subjects.\n\nPlease email e
xternal-relations@maths.ox.ac.uk to register to attend in person.\n\nThe l
ecture will be broadcast on the Oxford Mathematics YouTube Channel on Thur
sday 13 June at 5-6pm and any time after (no need to register for the onli
ne version).\n\nThe Oxford Mathematics Public Lectures are generously supp
orted by XTX Markets.\nSpeakers:\nOfra Magidor (University of Oxford)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/c9ae6a63-a1c9-4539-bb79-24fbd931c0
46/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Infinite Jesters: what can philosophers learn from a puzz
le involving infinitely many clowns? - Ofra Magidor and Alexander Kaiserma
n - Ofra Magidor (University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Open challenges at the intersection of Synthetic Biology and Mathe
matics - Dr Harrison Steel (University of Oxford)
DTSTART;VALUE=DATE-TIME:20240524T140000
DTEND;VALUE=DATE-TIME:20240524T150000
UID:https://new.talks.ox.ac.uk/talks/id/e3e97303-9bf1-4f7d-a35c-57500969c0
c0/
DESCRIPTION:\nSpeakers:\nDr Harrison Steel (University of Oxford)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/e3e97303-9bf1-4f7d-a35c-57500969c0
c0/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Open challenges at the intersection of Synthetic Biology
and Mathematics - Dr Harrison Steel (University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:More Pope-like than the Pope: modern mathematics movement in Czech
oslovakia - Helena Durnová (Masaryk University)
DTSTART;VALUE=DATE-TIME:20240529T170000
DTEND;VALUE=DATE-TIME:20240529T183000
UID:https://new.talks.ox.ac.uk/talks/id/cae923cf-b22c-4ba6-87f2-bfad011e24
bf/
DESCRIPTION:Modern mathematics movement of the early 20th century found it
s way into the teaching of mathematics across the world in the early post-
war period\, with Georges Papy and André Lichnerowicz leading the way in
Europe. In Czechoslovakia\, this transformation of mathematics education i
s known as “set-theoretical approach”. Indeed set theory is at the cor
e of Bourbakist transformation of the mathematical knowledge\, as exemplif
ied by their masterpiece Élements de Mathématique\, which became mathema
ticians’ manifesto. In the educational setting\, the adjectives “new
” and “modern” were found more appropriate\, but not so in Czechoslo
vakia. \n \nDirk de Bock’s recent book on the topic (Modern Mathematics:
An International Movement?\, Springer 2023) covers a lot of Modern Math\,
but Czechoslovakia is missing\, and here we are. Czechoslovakia is at the
heart of Europe\, perhaps the heart of Europe. Hence we connect to other
countries: Poland\, Hungary\, Soviet Union\, but also Belgium\, France\, S
weden (marginally)\, the Netherlands\, and Yugoslavia as a very special ca
se.\n\nThis seminar reports on a joint project of Helena Durnová\, Petra
Bušková (Masaryk University)\, Danny J. Beckers (Vrije Universiteit Amst
erdam)\, and Snezana Lawrence (Middlesex University).\nSpeakers:\nHelena D
urnová (Masaryk University)
LOCATION:Mathematical Institute (Lecture Room L4)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/cae923cf-b22c-4ba6-87f2-bfad011e24
bf/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:More Pope-like than the Pope: modern mathematics movement
in Czechoslovakia - Helena Durnová (Masaryk University)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Cytoneme-mediated morphogenesis - Prof Paul Bressloff (Dept of Mat
hematics\, Imperial College\, London)
DTSTART;VALUE=DATE-TIME:20240531T140000
DTEND;VALUE=DATE-TIME:20240531T150000
UID:https://new.talks.ox.ac.uk/talks/id/5a481226-6078-4299-b051-7e72872899
47/
DESCRIPTION:Morphogen protein gradients play an essential role in the spat
ial regulation of patterning during embryonic development. The most commo
nly accepted mechanism of protein gradient formation involves the diffusio
n and degradation of morphogens from a localized source. Recently\, an alt
ernative mechanism has been proposed\, which is based on cell-to-cell tran
sport via thin\, actin-rich cellular extensions known as cytonemes. It has
been hypothesized that cytonemes find their targets via a random search p
rocess based on alternating periods of retraction and growth\, perhaps med
iated by some chemoattractant. This is an actin-based analog of the search
-and-capture model of microtubules of the mitotic spindle searching for cy
tochrome binding sites (kinetochores) prior to separation of cytochrome pa
irs. In this talk\, we introduce a search-and-capture model of cytoneme-ba
sed morphogenesis\, in which nucleating cytonemes from a source cell dynam
ically grow and shrink until making contact with a target cell and deliver
ing a burst of morphogen. We model the latter as a one-dimensional search
process with stochastic resetting\, finite returns times and refractory pe
riods. We use a renewal method to calculate the splitting probabilities an
d conditional mean first passage times (MFPTs) for the cytoneme to be capt
ured by a given target cell. We show how multiple rounds of search-and-cap
ture\, morphogen delivery\, cytoneme retraction and nucleation events lead
to the formation of a morphogen gradient. We proceed by formulating the m
orphogen bursting model as a queuing process\, analogous to the study of t
ranslational bursting in gene networks. We end by briefly discussing curre
nt work on a model of cytoneme-mediated within-host viral spread.\nSpeaker
s:\nProf Paul Bressloff (Dept of Mathematics\, Imperial College\, London)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/5a481226-6078-4299-b051-7e72872899
47/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Cytoneme-mediated morphogenesis - Prof Paul Bressloff (De
pt of Mathematics\, Imperial College\, London)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Modeling the electromechanics of aerial electroreception - Dr Isaa
c Vikram Chenchiah (School of Mathematics University of Bristol)
DTSTART;VALUE=DATE-TIME:20240607T140000
DTEND;VALUE=DATE-TIME:20240607T150000
UID:https://new.talks.ox.ac.uk/talks/id/87e439fb-073b-4595-937a-807150c3d0
2f/
DESCRIPTION:Aerial electroreception is the ability of some arthropods (e.g
.\, bees) to detect electric fields in the environment. I present an overv
iew of our attempts to model the electromechanics of this recently discove
red phenomenon and how it might contribute to the sensory biology of arthr
opods. This is joint work with Daniel Robert and Ryan Palmer.\n\nSpeakers:
\nDr Isaac Vikram Chenchiah (School of Mathematics University of Bristol)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/87e439fb-073b-4595-937a-807150c3d0
2f/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Modeling the electromechanics of aerial electroreception
- Dr Isaac Vikram Chenchiah (School of Mathematics University of Bristol)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Brain mechanics in the Data era - Prof Antoine Jerusalem (Universi
ty of Oxford)
DTSTART;VALUE=DATE-TIME:20240614T140000
DTEND;VALUE=DATE-TIME:20240614T150000
UID:https://new.talks.ox.ac.uk/talks/id/10f8665c-34fd-400d-882b-cb8cb43142
0c/
DESCRIPTION:In this presentation\, we will review how the field of Mechani
cs of Materials is generally framed and see how it can benefit from and be
of benefit to the current progress in AI. We will approach this problemat
ic in the particular context of Brain mechanics with an application to tra
umatic brain injury in police investigations. Finally we will briefly show
how our group is currently applying the same methodology to a range of en
gineering challenges.\nSpeakers:\nProf Antoine Jerusalem (University of Ox
ford)
LOCATION:Mathematical Institute (L3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/10f8665c-34fd-400d-882b-cb8cb43142
0c/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Brain mechanics in the Data era - Prof Antoine Jerusalem
(University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Mathematical modelling to support New Zealand’s Covid-19 respons
e - Prof Mike Plank (University of Canterbury)
DTSTART;VALUE=DATE-TIME:20240617T110000
DTEND;VALUE=DATE-TIME:20240617T120000
UID:https://new.talks.ox.ac.uk/talks/id/c9a1d3bb-171e-4f04-a0b2-f617ffbf8e
69/
DESCRIPTION:In this talk\, I will describe some of the ways in which mathe
matical modelling contributed to the Covid-19 pandemic response in New Zea
land. New Zealand adopted an elimination strategy at the beginning of the
pandemic and used a combination of public health measures and border restr
ictions to keep incidence of Covid-19 low until high vaccination rates wer
e achieved. The low or zero prevalence for first 18 months of the pandemic
called for a different set of modelling tools compared to high-prevalence
settings. It also generated some unique data that can give valuable insig
hts into epidemiological characteristics and dynamics. As well as describi
ng some of the modelling approaches used\, I will reflect on the value mod
elling can add to decision making and some of the challenges and opportuni
ties in working with stakeholders in government and public health.
\nSpeakers:\nProf Mike Plank (University of Canterbury)
LOCATION:Mathematical Institute (L2)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/c9a1d3bb-171e-4f04-a0b2-f617ffbf8e
69/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Mathematical modelling to support New Zealand’s Covid-1
9 response - Prof Mike Plank (University of Canterbury)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:From Ronald Ross to ChatGPT: the birth and strange life of the ran
dom walk - Jordan Ellenberg - Jordan Ellenberg (University of Wisconsin-Ma
dison)
DTSTART;VALUE=DATE-TIME:20240626T170000
DTEND;VALUE=DATE-TIME:20240626T180000
UID:https://new.talks.ox.ac.uk/talks/id/81d8eb4c-60be-436d-97eb-0000679220
bb/
DESCRIPTION:Oxford Mathematics Public Lecture\n\nFrom Ronald Ross to ChatG
PT: the birth and strange life of the random walk - Jordan Ellenberg\nWedn
esday 26 June 2024\n5-6pm Andrew Wiles Building\, Mathematical Institute\,
Oxford\n\nBetween 1905 and 1910 the idea of the random walk\, now a major
topic in applied maths\, was invented simultaneously and independently by
multiple people in multiple countries for completely different purposes
– in the UK\, the story starts with Ronald Ross and the problem of mosqu
ito control\, but elsewhere\, the theory was being developed in domains fr
om physics to finance to winning a theological argument (really!).\n\nJord
an will tell some part of this story and also gesture at ways that random
walks (or Markov processes\, named after the theological arguer) underlie
current approaches to artificial intelligence\; he will touch on some of h
is own work with DeepMind and speculate about the capabilities of those sy
stems now and in the future.\n\nJordan Ellenberg is a Professor of Mathema
tics at the University of Wisconsin-Madison. He is the author of best-sell
ing works of non-fiction and fiction\, and has written and lectured extens
ively for a general audience about the wonders of mathematics for over fif
teen years.\n\nPlease email external-relations@maths.ox.ac.uk to register
to attend in person.\n\nThe lecture will be broadcast on the Oxford Mathem
atics YouTube Channel on Thursday 18 July at 5-6pm and any time after (no
need to register for the online version).\n\nThe Oxford Mathematics Public
Lectures are generously supported by XTX Markets.\nSpeakers:\nJordan Elle
nberg (University of Wisconsin-Madison)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/81d8eb4c-60be-436d-97eb-0000679220
bb/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:From Ronald Ross to ChatGPT: the birth and strange life o
f the random walk - Jordan Ellenberg - Jordan Ellenberg (University of Wis
consin-Madison)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:The Counting Project - Tim Harford - Tim Harford
DTSTART;VALUE=DATE-TIME:20240710T170000
DTEND;VALUE=DATE-TIME:20240710T180000
UID:https://new.talks.ox.ac.uk/talks/id/523cbcff-976a-4915-95a5-b763ab2c6a
6c/
DESCRIPTION:The Inaugural Vicky Neale Public Lecture\n\nThe Vicky Neale Pu
blic Lecture recognises the invaluable contribution to mathematical educat
ion of the late Vicky Neale. In this lecture\, economist and broadcaster T
im Harford looks at how data built the modern world - and how we can use i
t to build a better one.\n\nPlease email external-relations@maths.ox.uk to
register to attend in person.\n\nThe lecture will be broadcast on the Oxf
ord Mathematics YouTube Channel on Wednesday 31 July at 5-6pm and any time
after (no need to register for the online version).\n\nThe Vicky Neale Pu
blic Lectures are a partnership between the Clay Mathematics Institute\, P
ROMYS and Oxford Mathematics. The Oxford Mathematics Public Lectures are g
enerously supported by XTX Markets.\nSpeakers:\nTim Harford
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/523cbcff-976a-4915-95a5-b763ab2c6a
6c/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:The Counting Project - Tim Harford - Tim Harford
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Microswimmer motility and natural robustness in pattern formation:
the emergence and explanation of non-standard multiscale phenomena - Prof
. Mohit Dalwadi (Mathematical Institute)
DTSTART;VALUE=DATE-TIME:20241017T120000
DTEND;VALUE=DATE-TIME:20241017T130000
UID:https://new.talks.ox.ac.uk/talks/id/b41d02a6-a08b-4cb6-bbb6-97cf351ed9
f5/
DESCRIPTION:In this talk I use applied mathematics to understand emergent
multiscale phenomena arising in two fundamental problems in fluids and bio
logy.\n \nIn the first part\, I discuss an overarching question in develop
mental biology: how is it that cells are able to decode spatio-temporally
varying signals into functionally robust patterns in the presence of confo
unding effects caused by unpredictable or heterogeneous environments? This
is linked to the general idea first explored by Alan Turing in the 1950s.
I present a general theory of pattern formation in the presence of spatio
-temporal input variations\, and use multiscale mathematics to show how bi
ological systems can generate non-standard dynamic robustness for 'free' o
ver physiologically relevant timescales. This work also has applications i
n pattern formation more generally.\n \nIn the second part\, I investigate
how the rapid motion of 3D microswimmers affects their emergent trajector
ies in shear flow. This is an active version of the classic fluid mechanic
s result of Jeffery's orbits for inert spheroids\, first explored by Georg
e Jeffery in the 1920s. I show that the rapid short-scale motion exhibited
by many microswimmers can have a significant effect on longer-scale traje
ctories\, despite the common neglect of this motion in some mathematical m
odels\, and how to systematically incorporate this effect into modified ve
rsions of Jeffery's original equations.\nSpeakers:\nProf. Mohit Dalwadi (M
athematical Institute)
LOCATION:Mathematical Institute (Lecture Room 3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/b41d02a6-a08b-4cb6-bbb6-97cf351ed9
f5/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Microswimmer motility and natural robustness in pattern f
ormation: the emergence and explanation of non-standard multiscale phenome
na - Prof. Mohit Dalwadi (Mathematical Institute)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Novel multi-omics approaches to understand immune cell biology in
health and disease - Prof Rachael Bashford-Rogers (University of Oxford)
DTSTART;VALUE=DATE-TIME:20241018T110000
DTEND;VALUE=DATE-TIME:20241018T120000
UID:https://new.talks.ox.ac.uk/talks/id/17096184-6156-4f51-a871-ba0bcc8219
9a/
DESCRIPTION:Immunological health relies on a balance between the ability t
o mount an immune response against potential pathogens and tolerance to se
lf. However\, how we keep that balance in health and what goes wrong in di
sease is not well understood. Here\, I will describe combination of novel
experimental and computational approaches using multi-omics datasets\, ima
ging and functional experiments to dissect the role and defects in immune
cells across several disease areas in cancer and autoimmunity. We show how
shared mechanisms that are disrupted across diseases\, including cellular
\, migration\, immuno-surveillance\, regulation and activation\, as well a
s the immunological features associated with better prognosis and immunomo
dulation.\nSpeakers:\nProf Rachael Bashford-Rogers (University of Oxford)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/17096184-6156-4f51-a871-ba0bcc8219
9a/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Novel multi-omics approaches to understand immune cell bi
ology in health and disease - Prof Rachael Bashford-Rogers (University of
Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Effective elasticity and dynamics of helical filaments under distr
ibuted loads - Dr. Michael Gomez (Kings College London)
DTSTART;VALUE=DATE-TIME:20241024T120000
DTEND;VALUE=DATE-TIME:20241024T130000
UID:https://new.talks.ox.ac.uk/talks/id/ae17c88b-3581-4be0-813e-066b9dd357
4d/
DESCRIPTION:Slender elastic filaments with intrinsic helical geometry are
encountered in a wide range of physical and biological settings\, ranging
from coil springs in engineering to bacteria flagellar filaments. The equi
librium configurations of helical filaments under a variety of loading typ
es have been well studied in the framework of the Kirchhoff rod equations.
These equations are geometrically nonlinear and so can account for large\
, global displacements of the rod. This geometric nonlinearity also makes
a mathematical analysis of the rod equations extremely difficult\, so that
much is still unknown about the dynamic behaviour of helical rods under e
xternal loading.\n\nAn important class of simplified models consists of 'e
quivalent-column' theories. These model the helical filament as a naturall
y-straight beam (aligned with the helix axis) for which the extensional an
d torsional deformations are coupled. Such theories have long been used in
engineering to describe the free vibrations of helical coil springs\, tho
ugh their validity remains unclear\, particularly when distributed forces
and moments are present. In this talk\, we show how such an effective theo
ry can be derived systematically from the Kirchhoff rod equations using th
e method of multiple scales. Importantly\, our analysis is asymptotically
exact in the small-wavelength limit and can account for large\, unsteady d
isplacements. We then illustrate our theory with two loading scenarios: (i
) a heavy helical rod deforming under its own weight\; and (ii) axial rota
tion (twirling) in viscous fluid\, which may be considered as a simple mod
el for a bacteria flagellar filament. More broadly\, our analysis provides
a framework to develop reduced models of helical rods in a wide variety o
f physical and biological settings\, as well as yielding analytical insigh
t into their tensile instabilities.\nSpeakers:\nDr. Michael Gomez (Kings C
ollege London)
LOCATION:Mathematical Institute (Lecture Room 3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/ae17c88b-3581-4be0-813e-066b9dd357
4d/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Effective elasticity and dynamics of helical filaments un
der distributed loads - Dr. Michael Gomez (Kings College London)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Engineering Biology for Robust Turing Patterns - Prof Robert Endr
es (Imperial College London)
DTSTART;VALUE=DATE-TIME:20241025T110000
DTEND;VALUE=DATE-TIME:20241025T120000
UID:https://new.talks.ox.ac.uk/talks/id/d6713d44-bca6-48e6-9567-6dd8eec77e
43/
DESCRIPTION:Turing patterns have long been proposed as a mechanism for spa
tial organization in biology\, but their relevance remains controversial d
ue to the stringent fine-tuning often required. In this talk\, I will pres
ent recent efforts to engineer synthetic Turing systems in bacterial colon
ies\, highlighting both successes and limitations. While our three-node ge
ne circuit generates patterns\, challenges remain in extending these resul
ts to broader contexts. Additionally\, I will discuss our exploration of m
achine learning methods to address the inverse problem of pattern formatio
n\, helping the design process down the road. This work addresses the ongo
ing task in translating theory into robust biological applications\, offer
ing insights into both current capabilities and future directions.\nSpeake
rs:\nProf Robert Endres (Imperial College London)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/d6713d44-bca6-48e6-9567-6dd8eec77e
43/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Engineering Biology for Robust Turing Patterns - Prof Ro
bert Endres (Imperial College London)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Volcanic fissure localisation and lava delta formation: Modelling
of volcanic flows undergoing rheological evolution - Dr. Jesse Taylor West
(University of Bristol)
DTSTART;VALUE=DATE-TIME:20241031T120000Z
DTEND;VALUE=DATE-TIME:20241031T130000Z
UID:https://new.talks.ox.ac.uk/talks/id/ea4bc270-6d49-48fb-b8dc-69334e92c2
ed/
DESCRIPTION:In this talk\, I will present two volcanologically motivated m
odelling problems. In the first\, I will detail how thermoviscous localis
ation of volcanic eruptions is influenced by the irregular geometry of nat
ural volcanic fissures. Fissure eruptions typically start with the opening
of a linear fissure that erupts along its entire length\, following which
activity localises to one or more isolated vents within a few hours or da
ys. Previous work has proposed that localisation can arise through a therm
oviscous fingering instability driven by the strongly temperature dependen
t viscosity of the rising magma. I will show that\, even for relatively mo
dest variations of the fissure width\, a non-planar geometry supports stro
ngly localised steady states\, in which the wider parts of the fissure hos
t faster\, hotter flow\, and the narrower parts of the fissure host slower
\, cooler flow. This geometrically-driven localisation is different from\,
and typically more potent than\, the thermoviscous fingering localisation
observed in planar geometries. \n \nThe second problem concerns lava del
ta formation. A lava delta arises when a volcanic lava flow enters a body
of water\, extending the pre-eruption shoreline via the creation of new\,
flat land. A combination of cooling induced rheological changes and the re
duction in gravitational driving forces controls the morphology and evolut
ion of the delta. I will present shallow-layer continuum models for this p
rocess\, highlighting how different modes of delta formation manifest in d
ifferent late-time behaviours.\nSpeakers:\nDr. Jesse Taylor West (Universi
ty of Bristol)
LOCATION:Mathematical Institute (Lecture Room 3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/ea4bc270-6d49-48fb-b8dc-69334e92c2
ed/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Volcanic fissure localisation and lava delta formation: M
odelling of volcanic flows undergoing rheological evolution - Dr. Jesse Ta
ylor West (University of Bristol)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Applications of extreme statistics to cellular decision making and
signaling - Prof Alan Lindsay (University of Notre Dame)
DTSTART;VALUE=DATE-TIME:20241101T110000Z
DTEND;VALUE=DATE-TIME:20241101T120000Z
UID:https://new.talks.ox.ac.uk/talks/id/43cfc893-ab1d-43bb-9515-158d33a8b7
60/
DESCRIPTION:Cells must reliably coordinate responses to noisy external sti
muli for proper functionality whether deciding where to move or initiate a
response to threats. In this talk I will present a perspective on such ce
llular decision making problems with extreme statistics. The central premi
se is that when a single stochastic process exhibits large variability (un
reliable)\, the extrema of multiple processes has a remarkably tight distr
ibution (reliable). In this talk I will present some background on extreme
statistics followed by two applications. The first regards antigen discri
mination - the recognition by the T cell receptor of foreign antigen. The
second concerns directional sensing - the process in which cells acquire a
direction to move towards a target. In both cases\, we find that extreme
statistics explains how cells can make accurate and rapid decisions\, and
importantly\, before any steady state is reached.\nSpeakers:\nProf Alan Li
ndsay (University of Notre Dame)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/43cfc893-ab1d-43bb-9515-158d33a8b7
60/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Applications of extreme statistics to cellular decision m
aking and signaling - Prof Alan Lindsay (University of Notre Dame)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:History and highlights of the Kerala school of mathematics - Adity
a Kolachana (IIT Madras)
DTSTART;VALUE=DATE-TIME:20241104T143000Z
DTEND;VALUE=DATE-TIME:20241104T153000Z
UID:https://new.talks.ox.ac.uk/talks/id/497161a8-d70b-49b3-b2d2-028c2f9d27
80/
DESCRIPTION:During the 14th to the 16th centuries CE\, a succession of Ind
ian scholars\, collectively referred to as the Kerala school\, made remark
able contributions in the fields of mathematics and astronomy. Mādhava of
Saṅgamagrāma\, a gifted mathematician and astronomer\, is considered t
he founder of this school\, and is perhaps best known for discovering an i
nfinite series for pi\, among other achievements. Subsequently\, Mādhava'
s lineage of disciples\, consisting of illustrious names such as Parameśv
ara\, Dāmodara\, Nīlakaṇṭha\, Jyeṣṭhadeva\, Śaṅkara Vāriyar\
, Citrabhānu\, Acyuta Piṣaraṭi etc.\, made numerous important contrib
utions of their own in the fields of mathematics and astronomy. Later scho
lars of the Kerala school flourished up to the 19th century. This talk wil
l provide a historical overview of the Kerala school and highlight its imp
ortant contributions.\nSpeakers:\nAditya Kolachana (IIT Madras)
LOCATION:Mathematical Institute (L6)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/497161a8-d70b-49b3-b2d2-028c2f9d27
80/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:History and highlights of the Kerala school of mathematic
s - Aditya Kolachana (IIT Madras)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Functional\, neutral and selected heterogeneity in multi-cellular
populations and human tissues - Dr David Tourigny (University of Birmingha
m)
DTSTART;VALUE=DATE-TIME:20241108T110000Z
DTEND;VALUE=DATE-TIME:20241108T120000Z
UID:https://new.talks.ox.ac.uk/talks/id/d215e89c-e10b-4e66-a796-c6b394ecc8
92/
DESCRIPTION:No biological system involves a single cell functioning in iso
lation. Almost all consist of highly connected networks of interacting ind
ividuals\, which respond and adapt differently to signals and conditions w
ithin their local microenvironment. For example\, human tissues and their
cancers contain mosaics of genetic clones\, and the transcriptomic and met
abolic profiles from genetically identical cells are also highly heterogen
eous. As the full extent of multi-cellular heterogeneity is revealed by re
cent experimental advances\, computational and mathematical modelling can
begin to provide a quantitative framework for understanding its biological
implications. In this talk\, I will describe some functional aspects of m
ulti-cellular heterogeneity and explore the consequences for human health
and disease.\n\nSpeakers:\nDr David Tourigny (University of Birmingham)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/d215e89c-e10b-4e66-a796-c6b394ecc8
92/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Functional\, neutral and selected heterogeneity in multi-
cellular populations and human tissues - Dr David Tourigny (University of
Birmingham)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:The Seventeenth Brooke Benjamin Lecture 2024: The Elusive Singular
ity - Professor Peter Constantin (Princeton University)
DTSTART;VALUE=DATE-TIME:20241111T170000Z
DTEND;VALUE=DATE-TIME:20241111T180000Z
UID:https://new.talks.ox.ac.uk/talks/id/c660ef75-d299-455a-9885-f35ec355b0
e5/
DESCRIPTION:I will describe the open problems of singularity formation in
incompressible fluids. I will discuss a list of related models\, some resu
lts\, and some more open problems.\nSpeakers:\nProfessor Peter Constantin
(Princeton University)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/c660ef75-d299-455a-9885-f35ec355b0
e5/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:The Seventeenth Brooke Benjamin Lecture 2024: The Elusive
Singularity - Professor Peter Constantin (Princeton University)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Lane formation and aggregation spots in foraging ant - Dr Maria Br
una (University of Oxford)
DTSTART;VALUE=DATE-TIME:20241115T110000Z
DTEND;VALUE=DATE-TIME:20241115T120000Z
UID:https://new.talks.ox.ac.uk/talks/id/5d3b1cfe-8ce2-406d-a018-44ea1c75d8
89/
DESCRIPTION:We consider a system of interacting particles as a model for a
foraging ant colony\, where each ant is represented as an active Brownian
particle. The interactions among ants are mediated through chemotaxis\, a
ligning their orientations with the upward gradient of a pheromone field.
Unlike conventional models\, our study introduces a parameter that enables
the reproduction of two distinctive behaviours: the conventional Keller-S
egel aggregation and the formation of travelling clusters without relying
on external constraints such as food sources or nests. We consider the ass
ociated mean-field limit of this system and establish the analytical and n
umerical foundations for understanding these particle behaviours.\nSpeaker
s:\nDr Maria Bruna (University of Oxford)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/5d3b1cfe-8ce2-406d-a018-44ea1c75d8
89/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Lane formation and aggregation spots in foraging ant - Dr
Maria Bruna (University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Chance\, luck\, and ignorance: how to put our uncertainty into num
bers - David Spiegelhalter - Professor David Spiegelhalter (University of
Cambridge)
DTSTART;VALUE=DATE-TIME:20241120T170000Z
DTEND;VALUE=DATE-TIME:20241120T180000Z
UID:https://new.talks.ox.ac.uk/talks/id/6bd64a49-d907-4c58-8d98-411caa08ac
b5/
DESCRIPTION:Oxford Mathematics Public Lecture\n\nWe all have to live with
uncertainty about what is going to happen\, what has happened\, and why th
ings turned out how they did. We attribute good and bad events as ‘due
to chance’\, label people as ‘lucky’\, and (sometimes) admit our ign
orance. I will show how to use the theory of probability to take apart al
l these ideas\, and demonstrate how you can put numbers on your ignorance\
, and then measure how good those numbers are. Along the way we will look
at three types of luck\, and judge whether Derren Brown was lucky or unluc
ky when he was filmed flipping ten Heads in a row.\n\nDavid Spiegelhalter
was Cambridge University's first Winton Professor of the Public Understand
ing of Risk. He has appeared regularly on television and radio and is the
author of several books\, the latest of which is The Art of Uncertainty: H
ow to Navigate Chance\, Ignorance\, Risk and Luck (Penguin\, September 202
4).\n\nPlease email external-relations@maths.ox.ac.uk to register to atten
d in person.\n\nThe lecture will be broadcast on the Oxford Mathematics Yo
uTube Channel on Wednesday 11 December at 5-6pm and any time after (no nee
d to register for the online version).\n\nThe Oxford Mathematics Public Le
ctures are generously supported by XTX Markets.\nSpeakers:\nProfessor Davi
d Spiegelhalter (University of Cambridge)
LOCATION:Mathematical Institute (Lecture Theatre 1)\, Woodstock Road OX2 6
GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/6bd64a49-d907-4c58-8d98-411caa08ac
b5/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Chance\, luck\, and ignorance: how to put our uncertainty
into numbers - David Spiegelhalter - Professor David Spiegelhalter (Unive
rsity of Cambridge)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Bifurcations\, pattern formation and multi-stability in non-local
models of interacting species - Dr Valeria Giunta (Swansea University)
DTSTART;VALUE=DATE-TIME:20241122T110000Z
DTEND;VALUE=DATE-TIME:20241122T120000Z
UID:https://new.talks.ox.ac.uk/talks/id/c704aad8-d778-42ca-a662-235ca6ef0a
d7/
DESCRIPTION:Understanding the mechanisms behind the spatial distribution\,
self-organisation and aggregation of organisms is a central issue in both
ecology and cell biology. Since self-organisation at the population level
is the cumulative effect of behaviours at the individual level\, it requi
res a mathematical approach to be elucidated.\nIn nature\, every individua
l\, be it a cell or an animal\, inspects its territory before moving. The
process of acquiring information from the environment is typically non-loc
al\, i.e. individuals have the ability to inspect a portion of their terri
tory. In recent years\, a growing body of empirical research has shown tha
t non-locality is a key aspect of movement processes\, while mathematical
models incorporating non-local interactions have received increasing atten
tion for their ability to accurately describe how interactions between ind
ividuals and their environment can affect their movement\, reproduction ra
te and well-being. In this talk\, I will present a study of a class of adv
ection-diffusion equations that model population movements generated by no
n-local species interactions. Using a combination of analytical and numeri
cal tools\, I will show that these models support a wide variety of spatio
-temporal patterns that are able to reproduce segregation\, aggregation an
d time-periodic behaviours commonly observed in real systems. I will also
show the existence of parameter regions where multiple stable solutions co
exist and hysteresis phenomena.\nOverall\, I will describe various methods
for analysing bifurcations and pattern formation properties of these mode
ls\, which represent an essential mathematical tool for addressing fundame
ntal questions about the many aggregation phenomena observed in nature.\n\
nSpeakers:\nDr Valeria Giunta (Swansea University)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/c704aad8-d778-42ca-a662-235ca6ef0a
d7/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Bifurcations\, pattern formation and multi-stability in n
on-local models of interacting species - Dr Valeria Giunta (Swansea Univer
sity)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Truth Be Told: How To Interpret Past Mathematicians - A. C. Paseau
(University of Oxford)\, Fabian Pregel (University of Oxford)
DTSTART;VALUE=DATE-TIME:20241127T170000Z
DTEND;VALUE=DATE-TIME:20241127T183000Z
UID:https://new.talks.ox.ac.uk/talks/id/57ed5196-459d-498d-b0df-e952143592
dc/
DESCRIPTION:How should we interpret past mathematicians who may use the sa
me vocabulary as us but with different meanings\, or whose philosophical o
utlooks differ from ours? Errors aside\, it is often assumed that past mat
hematicians largely made true claims—but what exactly justifies that ass
umption?\n\nIn this talk\, we will explore these questions through general
philosophical considerations and three case studies: 19th-century analysi
s\, 18th-century geometry\, and 19th-century matricial algebra. In each c
ase\, we encounter a significant challenge to supposing that the mathemati
cians in question made true claims. We will show how these challenges can
be addressed and overcome.\nSpeakers:\nA. C. Paseau (University of Oxford)
\, Fabian Pregel (University of Oxford)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/57ed5196-459d-498d-b0df-e952143592
dc/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Truth Be Told: How To Interpret Past Mathematicians - A.
C. Paseau (University of Oxford)\, Fabian Pregel (University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:OCIAM Speaker - Prof Anđela Šarić - Prof Anđela Šarić (IST A
ustria)
DTSTART;VALUE=DATE-TIME:20241128T120000Z
DTEND;VALUE=DATE-TIME:20241128T130000Z
UID:https://new.talks.ox.ac.uk/talks/id/79d66fa0-17d4-4ba0-813d-2851689703
92/
DESCRIPTION:\nSpeakers:\nProf Anđela Šarić (IST Austria)
LOCATION:Mathematical Institute (Lecture Room 3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/79d66fa0-17d4-4ba0-813d-2851689703
92/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:OCIAM Speaker - Prof Anđela Šarić - Prof Anđela Šari
ć (IST Austria)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Algebraic approaches in the study of chemical reaction networks -
Dr Murad Banaji (University of Oxford)
DTSTART;VALUE=DATE-TIME:20241129T110000Z
DTEND;VALUE=DATE-TIME:20241129T120000Z
UID:https://new.talks.ox.ac.uk/talks/id/3cbbedd4-2b81-4d9d-99d4-4da01a8218
ca/
DESCRIPTION:Underlying many biological models are chemical reaction networ
ks (CRNs)\, and identifying allowed and forbidden dynamics in reaction net
works may give insight into biological mechanisms. Algebraic approaches ha
ve been important in several recent developments. For example\, computatio
nal algebra has helped us characterise all small mass action CRNs admittin
g certain bifurcations\; allowed us to find interesting and surprising exa
mples and counterexamples\; and suggested a number of conjectures. Progres
s generally involves an interaction between analysis and computation: on t
he one hand\, theorems which recast apparently difficult questions about d
ynamics as (relatively tractable) algebraic problems\; and on the other\,
computations which provide insight into deeper theoretical questions. I'll
present some results\, examples\, and open \nquestions\, focussing on two
domains of CRN theory: the study of local bifurcations\, and the study of
multistationarity.\nSpeakers:\nDr Murad Banaji (University of Oxford)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/3cbbedd4-2b81-4d9d-99d4-4da01a8218
ca/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Algebraic approaches in the study of chemical reaction ne
tworks - Dr Murad Banaji (University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Chaotic flows in polymer solutions: what’s new? - Prof. Rich Ker
swell (University of Cambridge)
DTSTART;VALUE=DATE-TIME:20241205T120000Z
DTEND;VALUE=DATE-TIME:20241205T130000Z
UID:https://new.talks.ox.ac.uk/talks/id/624b341e-bdaa-4a63-b7e6-e723b9bd00
ef/
DESCRIPTION:\nSpeakers:\nProf. Rich Kerswell (University of Cambridge)
LOCATION:Mathematical Institute (Lecture Room 3)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/624b341e-bdaa-4a63-b7e6-e723b9bd00
ef/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Chaotic flows in polymer solutions: what’s new? - Prof.
Rich Kerswell (University of Cambridge)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
BEGIN:VEVENT
SUMMARY:Spatial mechano-transcriptomics of mouse embryogenesis - Prof Adr
ien Hallou (University of Oxford)
DTSTART;VALUE=DATE-TIME:20241206T110000Z
DTEND;VALUE=DATE-TIME:20241206T120000Z
UID:https://new.talks.ox.ac.uk/talks/id/b6460ab9-cd3f-4937-9700-7ac6a735b1
04/
DESCRIPTION:Advances in spatial profiling technologies are providing insig
hts into how molecular programs are influenced by local signalling and env
ironmental cues. However\, cell fate specification and tissue patterning i
nvolve the interplay of biochemical and mechanical feedback. Here\, we pro
pose a new computational framework that enables the joint statistical anal
ysis of transcriptional and mechanical signals in the context of spatial t
ranscriptomics. To illustrate the application and utility of the approach\
, we use spatial transcriptomics data from the developing mouse embryo to
infer the forces acting on individual cells\, and use these results to ide
ntify mechanical\, morphometric\, and gene expression signatures that are
predictive of tissue compartment boundaries. In addition\, we use geoaddit
ive structural equation modelling to identify gene modules that predict th
e mechanical behaviour of cells in an unbiased manner. This computational
framework is easily generalized to other spatial profiling contexts\, prov
iding a generic scheme for exploring the interplay of biomolecular and mec
hanical cues in tissues.\nSpeakers:\nProf Adrien Hallou (University of Oxf
ord)
LOCATION:Mathematical Institute (L5)\, Woodstock Road OX2 6GG
TZID:Europe/London
URL:https://new.talks.ox.ac.uk/talks/id/b6460ab9-cd3f-4937-9700-7ac6a735b1
04/
BEGIN:VALARM
ACTION:display
DESCRIPTION:Talk:Spatial mechano-transcriptomics of mouse embryogenesis -
Prof Adrien Hallou (University of Oxford)
TRIGGER:-PT1H
END:VALARM
END:VEVENT
END:VCALENDAR