Covalent TCR-peptide-MHC interactions redirect T cell fate in the thymus

Stephen Daley is a Senior Research Fellow in Immunology at Queensland University of Technology (QUT), Brisbane, Australia. He trained and practiced as a veterinarian (BVSc 2000) before completing a DPhil at the Sir William Dunn School of Pathology (DPhil 2007). He returned to Australia for postdoctoral training at the Australian National University in Canberra investigating autoimmune disease. He was recruited to Monash University, where he led research from 2015 to 2019, before moving to QUT in 2020. His research focuses on T cell biology, especially the T cell antigen receptor, thymic selection, and autoimmune disease, using techniques including flow cytometry, mouse genetics, transplantation, and bioinformatics. Working with clinicians, bioinformaticians, and structural biologists, he is testing the idea that autoimmune disease originates in the thymus, where T cells develop.