Multiomic analysis of the human gut microbiome in autoimmune disease

Special Visiting Scientist Seminar

The microbial residents of the human gut have profound effects on the development and functioning of the immune system. Due to the complex nature of human-microbe interactions, multiomic analyses in which the genes and functional outputs of microbes and host are analysed together, permit greater understanding of the etiology of autoimmune disorders.In this talk, I will review current methods for multiomic microbiome human population studies, showing examples of host and microbial molecular profiles used to understand mechanisms of inflammation in the gut.
Kevin Bonham received a Bachelor of Science in Biochemistry and Cell Biology from the University of California, San Diego, and obtained his PhD in Immunology from Harvard University, where he studied the cell biology of macrophages and the biochemistry of toll-like receptor signalling. His postdoctoral work has focused on microbial genomics in multispecies communities such as cheese rinds and the human gut, as well as STEM education and the gender gap in computational biology.