Targeting IL-13 as a host-directed therapy against ulcerative colitis

For her PhD and Postdoctoral position Claire’s research focused on understanding the role of host immune responses to both infectious disease such as Helminthiasis, Leishmaniasis and Tuberculosis and non-communicable disease such as Inflammatory Bowel Disease, which she will present here. As an emerging researcher, her current research aims at understanding host immune responses to HIV-related fungal infections. Pneumocystis jirovecii is an opportunistic fungal pathogen of immunocompromised patients and is a common cause of pneumonia and death in patients with HIV/AIDS. Claire’s group investigates the immune response to Pneumocystis and other fungal infections prevalent on the African continent and the role other organisms, such as Mycobacterium tuberculosis play in infection. There are very few researchers dissecting the immune mechanisms of fungal infections in Africa and local research in this area could provide critical new insights into the mechanisms of disease. Claire will also provide a brief overview of this work