ADP-ribosylation signalling in regulation of genome stability
Dr Ahel’s lab employs a combination of structural studies, cell biology, and animal models to study cellular responses to DNA damage. In particular, their area of focus is on regulation of proteins involved in DNA repair and genome stability by ADP-ribosylation, a post-translational protein modification catalyzed by a family of enzymes called poly(ADP-ribose) polymerases (PARPs). PARPs have been linked to a number of cellular pathways including DNA repair, modulation of chromatin structure, apoptosis, and transcription
Date: 27 February 2017, 13:00 (Monday, 7th week, Hilary 2017)
Venue: Dorothy Crowfoot Hodgkin Building, off South Parks Road OX1 3QU
Venue Details: Main seminar room
Speaker: Dr Ivan Ahel (Sir William Dunn School of Pathology, University of Oxford)
Organising department: Department of Biochemistry
Organiser: OUBS (Department of Biochemistry, University of Oxford)
Organiser contact email address:
Part of: OUBS
Booking required?: Not required
Audience: Members of the University only
Editor: Christophe Chapard