Single-cell and epigenetic approaches to define and regulate macrophages in atherosclerosis
In our work we are pursuing a better understanding of macrophage functioning in atherosclerosis and identification of approaches to suppress their detrimental effects in disease. In my talk I will discuss our recent progress using single cell RNAseq of human atherosclerotic plaques to define immune cell populations and their characteristics. Moreover, we are performing studies to identify epigenetic enzymes that are relevant in regulating macrophages in atherosclerotic disease.
Date: 7 October 2019, 12:00 (Monday, 0th week, Michaelmas 2019)
Venue: Kennedy Institute of Rheumatology, Headington OX3 7FY
Venue Details: Bernard Sunley Lecture Theatre
Speaker: Professor Menno de Winther (Professor of Vascular Immune Cell Biology at the Academic Medical Center of the University of Amsterdam)
Organising department: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS)
Organiser: Jennifer Pope (Kennedy Institute of Rheumatology)
Organiser contact email address:
Host: Professor Claudia Monaco (Kennedy Institute of Rheumatology, Roosevelt Drive, Oxford OX3)
Part of: Kennedy Institute Seminars
Booking required?: Not required
Audience: Public
Editor: Jennifer Pope