What’s lipids got to do with it? What’s lipids, but a second-hand emulsion?
Integral membrane proteins that are embedded in the cellular plasma membrane make up the vast majority of all approved drug targets. However, the contributions of the membrane lipids to the function and behavior of these membrane-embedded proteins have for years been neglected. Often the membrane itself is seen as just a ‘scaffold’ to hold the protein in place. Using a range of integrated computational and experimental methods (several developed specifically for this project), we explore the interactions between membrane proteins and their surrounding lipid environments to reveal just how intricate, detailed, and balanced the relationship is.
Date: 1 February 2024, 15:00 (Thursday, 3rd week, Hilary 2024)
Venue: Dorothy Crowfoot Hodgkin Building, off South Parks Road OX1 3QU
Venue Details: Phase 1 Ground Floor Main Seminar Room (20-026)
Speaker: Dr. Tim Carpenter (Lawrence Livermore National Laboratory)
Organising department: Department of Biochemistry
Organiser: William Rochira (University of Oxford)
Organiser contact email address: william.rochira@bioch.ox.ac.uk
Host: William Rochira (University of Oxford)
Part of: SBCB Seminar Series
Booking required?: Not required
Audience: Members of the University only
Editor: William Rochira